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SIRS blood glucose in children with pneumonia,[link widoczny dla zalogowanych], CRP and PLT,[link widoczny dla zalogowanych], and its significance

4.459,[link widoczny dla zalogowanych], P <O. 05). 3 Discussion pediatric pneumonia is most common illnesses, severe pneumonia is 4, JL common cause of death, history of severe pneumonia that is the bacteria, viruses or other microorganisms results, SIRS put forward the concept of evolution as revealed severe pneumonia in the pathogenesis of MODS. SIRS is triggered by a variety of systemic injury response. Non-clinical infections, including infection and two cases, the main clinical feature of sustained high metabolism, and systemic hyperdynamic circulation excessive inflammatory response l2], and can lead to MODS. Our results show that children with pneumonia complicated by SIRS blood glucose and CRP levels were significantly higher than the pneumonia combined SIRS and control group patients (P <0.01), PLT counts were significantly decreased (Pd0.01), but not SIRS pneumonia combined blood glucose and PLT count and the control group was not statistically significant. Department of pneumonia when SIRS continued high metabolic state, body glucose use of limited raw sugar endogenous amino acids (pyruvate) and liver glycogen during active gluconeogenesis caused by high blood sugar, etc., while the excessive inflammatory response can be expressed as CRP increased significantly Ez-~]. Under normal circumstances, the body of the formation and destruction of PLT has a sound regulatory mechanism to maintain the blood PLT count at a certain level (100 × 10. ~ 300 × 10. / L). In the early stages of the body hit, mainly through the reduction of the release of PLT PLT storage compensatory spleen, and small storage capacity in the bone marrow PLT, PLT should be restored by bone marrow to generate the level of need 3 ~ 4d old time, early changes in PLT count for judging the severity and prognosis of more meaningful, the body blow suffered by the larger, PLT destruction more. Reduce the degree of PLT count more obvious impact on the tissues and organs of the more serious, the worse the prognosis Es]. This observed. Children with non-SIRS group of people's homes glucose, PLT and no significant difference between the control group, while CRP is a significant difference (P-~ 0.05), show that the general decline in lung PLT, blood glucose can only occur when SIRS, CRP were increased, PLT were decreased, and consistent with the diagnosis of SIRS change the number of items, s group at different stages of glucose and CRP were higher than the S group, PLT were lower than the S group, and sustainable for a long time. The article also observed that, S and S groups than in the 72h 24h, when the PLT significantly decreased (P-<0.05), and S group decreased, the difference was significant (P-40.01), which is Because the initial spleen and bone marrow play a compensatory role in the PLT, and the late result of a significant decompensation. Therefore, blood glucose, CRP and PLT helps to fully reflect the joint determination of the clinical characteristics of SIRS, which accurately assess the condition of the critical level. Occurrence and severity of SIRS and infection severity and incidence of MODS was significantly correlated. None of this group of non-occurrence of SIRS MODS, and SIRS groups in the S group was significantly higher than that of s MODS group (P <0.05), and blood glucose in 72h, CRP remained at significantly higher on day 5, PLT count 72h decline is still continuing, suggesting that blood glucose, CRP increased and sustained continuous decline in PLT count indicates a possible occurrence of MODS. This is as soon as possible to take measures to reduce high blood sugar, control inflammation and prevent further deterioration of great significance to the development of MODS.
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