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Czw 13:29, 10 Mar 2011
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Temat postu: mbt scarpe prezzi Endocrine function of vascular e

Endocrine function of vascular endothelial


It with the heart, blood vessels, endocrine function are important, they can produce and secrete more than ten kinds of raw land flail flail quality of life, on the regulation of blood pressure and body fluid balance has an important role in various high blood pressure, m, cerebrovascular, and other multi- kinds of pain mechanisms hair bereavement has an important pathophysiological significance. Therefore, as the representative of endothelin in vascular endothelial contraction factor (EDCF),[link widoczny dla zalogowanych], to fluoride oxide (NO) as the representative of the vascular relaxing factor (EDRF), the natriuretic peptide family and other buildings, together form a new research field, that is, * Vascular system with the endocrine function, it not only has the role of circulating hormones, but also play its part the effects of hormones to autocrine, paracrine, or endocrine cells secrete the whole body (hemoerine) Ha Kyu way to recover the body, regulate body lying , vascular bed tension and blood pressure. Put forward the concept of the circulatory system endocrine, not only enrich and expand the study of endocrine solid content and scope, but also for cardiovascular disease basic and clinical research provides a broad prospect and application build path. 9O vascular endocrinology is the world's blood vessels and endocrinology research Endocrinology and Metabolism Academic large basket Vascular endothelial times Bukui body, the surface area of about 400m, mostly in the capillaries, in the adults weighing about 1.5kg,[link widoczny dla zalogowanych], including about 1.2 × 10 can produce a variety of vasoactive substances, into a variety of endocrine persuade Wei, paracrine and autocrine organ, therefore, vascular endothelium is the body's largest endocrine gland. Because of its special position in which the king, through different mechanisms of static 】 and biochemical information, to release the ideological quality of vascular activity, cytokines and growth factors to regulate the immune response,[link widoczny dla zalogowanych], the blood vascular bed of the tension unit buildings; 100,730 in the project profiles of Medical Sciences, Peking Union Medical College of Endocrinology, Beijing Union Medical College Hospital. monograph . condensate process. the last decade, endothelial cells progressed very quickly, people's understanding of the endothelial cells are too large to deepen and prove the endothelial cells and vascular smooth muscle cells between the buildings is closely related to a variety of cells in vivo, they are constrained by each other each other to heap holding the body regulate normal physiological function of mouth]. vascular endothelial cells have an active endocrine functions in the body plays an important role in regulating the metabolism of buildings. Under normal physiological conditions, they maintain vascular tone and the child the stability of local blood flow, and in disease states, they secrete or metabolic diseases, abnormal Tong impact the occurrence and development. endothelin secretion of vascular endothelial cells is a powerful vasoconstrictor peptide mouth], and activation of calcium channels by increase the extension of ion flow, and promote contraction of vascular smooth muscle cells. In endothelial injury, increased the synthesis or release, and vascular smooth muscle cells in their receptor binding,[link widoczny dla zalogowanych], adjust the tension of the blood vessels of vascular contraction, at the same time as a growth factor, endothelin by stimulating the proliferation of vascular smooth muscle cells, participate in and promote the occurrence and development of hypertension. fluoride oxide (NO), prostacyclin (PGI) is the relaxation factor produced by endothelial cells, have a strong degree of vasodilatation antiplatelet aggregation function pull their points cut by cGMP or cAMP to reduce every concentration of intracellular calcium or blocking calcium influx, the relaxation of smooth muscle cell population]. In addition, vascular endothelial relaxing factor with the shrinkage factor between the feedback regulator of vascular tone of the child who is also an important role. Because the endothelial vascular smooth muscle cells by sounds of diastolic function and the role of membrane hyperpolarization, and therefore endothelial hyperpolarizing factor (endothe ~ um-derivedhyperpolar-iz_mgfactor, EDI -IF) is also involved in boat mediated endothelial function in vascular smooth muscle relaxation _.j. EDHF soil smooth muscle cells can be activated potassium channel, hyperpolarizing it, and then close the calcium channels, preventing calcium influx, so that relaxation of smooth muscle cells. Endothelial contraction or relaxation through the other guests with the regulation of vascular tension factors, normal child who vasomotor function. Currently, it is recognized that vascular endothelium is very important to the glands, endothelial dysfunction, endothelial relaxing factor with the shrinkage factor regulation and function of the secretion of the imbalance,[link widoczny dla zalogowanych], and a serious threat to human health, several common Tanbing, such as hypertension, atherosclerosis, myocardial ischemia and other vascular tumors of sputum pain in Xiamen, autoimmune diseases are all closely related, so , vascular endothelial basic and clinical research has been
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