Magnesium sulfate in the treatment and prevention -

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Magnesium sulfate in the treatment and prevention of eclampsia Reconsideration Application

Renal excretion. Therefore, serum magnesium concentration and dose per hour infusion, infusion rate and maternal body weight and kidney function are closely related. 4 magnesium sulfate 1O years of hospital clinical approach to conventional treatment methods are: eclampsia magnesium sulfate to prevent and control the amount of daily 2og, discretion, reduce the dose the next day, with 15 ~ / 24h can be. Application of shock load, also known as the first volume, 25% magnesium sulfate 20ml (5g) in 5% glucose solution in 20ml, 15min end within the rapid intravenous drip, the serum magnesium concentration in 15min, then up to the level of effective treatment with 5% glucose liquid the addition of 500ml of 25% magnesium sulfate 30m1 (7.5g) intravenous infusion, infusion rate control in 25 to 30 drops per minute, intravenous infusion of 2 groups containing 7.5g of magnesium sulfate the same liquid, dropping speed just 5h1 group End of Group 2 drops of liquid 10h, 1.5g of magnesium sulfate injection per hour to maintain blood magnesium levels, patients with severe preeclampsia the first 24h of magnesium sulfate can be used to 25 to 39, the fastest not> 2V-, / h. Night plus sedation patients can rest, this method several days of continuous use per day, to the patient symptoms, blood Author: 432100 Xiaogan pressure control Central Hospital of Gynecology and Obstetrics, after the withdrawal of urine protein was negative, and according to the patient appropriate time to terminate pregnancy. 5, magnesium sulfate magnesium sulfate toxicity toxicity is closely related with the serum magnesium concentration, treatment of eclampsia and poisoning drawback is that the effective concentration of serum magnesium concentration is extremely similar, so they asked to closely monitor the drug of breath, urine, knee reflex. Poisoning first appeared in the knee reflex. Medication must be present during the patellar reflex? Breathing> 16 times / rain, urine volume 25ml / h, using the process of attention to understand the feeling of patients, such as patients perceived dyspnea, limb muscle weakness, double vision, language is unclear or knee reflex, magnesium sulfate injection should be stopped on the BU immediately intravenous glucose Portugal calcium 1g,[link widoczny dla zalogowanych], to alleviate the symptoms of poisoning. Under normal circumstances, maternal injection of load after the skin may have a transient fever and abnormal heart rate response, without treatment, can relieve itself. 6, the general principle of treatment (1) to recognize that excessive use of magnesium sulfate, the input too fast will cause respiratory depression and cardiac arrest caused as a dangerous drug. (2) magnesium sulfate inhibited the activity at the neuromuscular interface, the main treatment is to prevent seizures. It is not blood pressure medicine, if the diastolic blood pressure ≥ ll0mmHg or MAP> 140mmHg need to use antihypertensive drugs. ... (3), mainly from the renal excretion of magnesium sulfate, if decreased urine output, reducing the amount of patients, the time when the increased use of diuretics. (4) Magnesium sulfate overdose or poisoning, can be antagonistic intravenous calcium gluconate 1g. (5) Magnesium sulfate has the advantages of increased uterine blood flow, protective effect on the fetus and improve the prognosis of fetal infants. 71O years back to my hospital from 1991 to 2001, 1O years, in order to receive patients with severe pre-eclampsia, no case occurred during the hospitalization of eclampsia. The total number of patients with eclampsia 216 patients treated, the incidence rate was 0.93% in the total number of obstetric hospital (216/23069), which pre-eclampsia 9O cases, 95 cases of intrapartum eclampsia, postpartum eclampsia 31 Bay J, eclampsia patients in the hospital transferred to the county and township. Magnesium sulfate are the preferred treatment, the amount of 25-3Og, 1O years of the same medication methods. Supplemented with sedation, blood pressure, expansion, correct dehydration and acid treatment and timely termination of pregnancy, maternal mortality is only 1 case of eclampsia. Because of the strict control of magnesium sulfate for every I, I, when the infusion volume, and close observation of patients with respiratory, 24h and monitoring fluid intake and output and blood magnesium concentration knee reflex, no case of magnesium sulfate poisoning. Therefore, if a more comprehensive understanding of the drug and medical management of the patient carefully during the treatment, its application is safe and reliable. I attended the hospital in the classification of Management Review, he had to go over the county and township hospitals in the region specifically to understand a bit of magnesium sulfate and the application of pregnancy-induced hypertension patients. Common problem is lack of knowledge on this drug, Qiang afraid of its side effects, inadequate dosage and method of properly, do not achieve effective therapeutic blood concentrations of magnesium, often difficult to control recurrent eclampsia and referral of cases. This paper describes a more comprehensive application of magnesium sulfate in all aspects, as long as the drug has a more comprehensive understanding and grasp of the principles of treatment and the principles of the poisoning, the less still a bold primary hospital for clinical and Hope this helps grass-roots hospital obstetrician.

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